Carlo Vittorio Cannistraci is a theoretical engineer, Zhou Yahui Chair Professor, Chief Scientist at the Tsinghua Laboratory of Brain and Intelligence (THBI), Director of the Center for Complex Network Intelligence (CCNI) at THBI and member of the Department of Computer Science, Department of Physics and Department of Biomedical Engineering at the Tsinghua University, Beijing, China. Carlo’s area of research embraces information theory, machine learning and physics of complex systems and networks including also applications in systems biomedicine and neuroscience. Nature Biotechnology selected Carlo’s article (Cell 2010) on machine learning in developmental biology to be nominated in the list of 2010 notable breakthroughs in computational biology. Circulation Research featured Carlo’s work (Circulation Research 2012) on leveraging a cardiovascular systems biology strategy to predict future outcomes in heart attacks, commenting: “a space-aged evaluation using computational biology”. The Technical University Dresden honoured Carlo of the Young Investigator Award 2016 in Physics for his work on the local-community-paradigm theory and link prediction in monopartite and bipartite networks. In 2017, Springer-Nature scientific blog highlighted with an interview to Carlo his study on “How the brain handles pain through the lens of network science”. The American Heart Association covered on its website the chronobiology discovery of Carlo on how the sunshine affects the risk and time onset of heart attack. In 2018, Nature Communications featured Carlo’s article entitled “Machine learning meets complex networks via coalescent embedding in the hyperbolic space” in the selected interdisciplinary collection of recent research on complex systems. In 2019, Scientific Reports selected Carlo’s interview between all their Editors to represent the journal in the social media. In 2019, Carlo won the Shanghai 1000 talents plan award, sponsored by CAS-MPG Partner Institute for Computational Biology. In 2020, Carlo was awarded of the Zhou Yahui Chair Professorship of Tsinghua University. In 2021, Carlo’s won the National high-level talent program award from the Minister of Science of China.