Adeeb Noor is an assistant professor in the faculty of computing and information technology at King Abdulaziz University, Jeddah and the IT director of King Abdulaziz University Hospital. He received his PhD in bioinformatics from the University of Colorado at Boulder in 2015, where he did his PhD under the supervision of Prof James Martin and Michel Dumontier. His work areas include data integration in bioinformatics, drug mechanisms, pharmacovigilance, and precision medicine.
Dr. Noor is currently working on mining patient data at King Abdulaziz University Hospital to improve the healthcare. He is also a part of a project that applies next-generation DNA sequencing (NGS) technique to study rare diseases, adverse drug events and pharmacogenomics.
Adverse drug events (ADEs), which often are caused by drug interactions, may result in morbidity, mortality, and increased healthcare expenditures. As the role of drug therapy continues to expand and polypharmacy becomes more common, the prevalence of ADEs also increases, potentially limiting the therapeutic benefits of medication therapy.
Indeed, identifying ADEs before drugs reach the market has been extremely challenging due to the limited availability of clinical studies, shortcomings within study designs, limited accessibility of drug interaction information due to storage in disparate sources, and omissions in interactions reporting within information sources, especially regarding their mechanisms and clinical significance.
In this talk, I will describe an integrative approach to medication safety using semantic web technologies. Semantic Web is not only useful for domain analysis, but can also be used to inform strategies for ADEs prevention. I will show how this approach can be useful for clinicians and researchers to gain some foresight into the likelihoods and causes of ADEs.